Document Detail

An objective method for grading of distal disease in the grafted coronary arteries.
MedLine Citation:
PMID:  17669896     Owner:  NLM     Status:  MEDLINE    
The impact of diffuseness of coronary artery disease on the outcome of coronary bypass grafting remains unclear due to the absence of an objective grading system for diffuseness. This study proposes a system and validates it by transit time flow measurements. All patients operated upon by the author from July 2004 to August 2006 were enrolled in the study. The patients who had procedures other than isolated coronary bypass grafting were excluded. This resulted in a set of 186 (151 male and 35 female) patients with a mean age of 59.55 years. Those vessels which had endarterectomies, on-lay patches, multiple/sequential grafts to a single artery were removed from analysis. The diffuseness of distal disease was graded from 0 to 3 on the basis of (i) the size of vessel and (ii) the number as well as significance of atheromatous lesions distal to the graft. The correlation analysis showed a moderate positive correlation between pulsitility index and grade of diffuseness and a moderate negative correlation between graft flow and grade of diffuseness (P<0.0001). This study shows that the proposed method of grading provides an objective and reliable system for the assessment of severity of distal disease in the grafted coronary arteries.
Anjum Jalal
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Publication Detail:
Type:  Journal Article     Date:  2007-05-15
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  6     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-02     Completed Date:  2007-08-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  451-5     Citation Subset:  IM    
Division of Cardiothoracic Surgery, King Khalid University Hospital, Riyadh, Saudi Arabia.
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MeSH Terms
Blood Flow Velocity
Coronary Artery Bypass*
Coronary Artery Disease / classification,  pathology*,  surgery
Coronary Circulation*
Coronary Vessels / pathology*
Intraoperative Period
Middle Aged
Pulsatile Flow
Comment In:
Interact Cardiovasc Thorac Surg. 2007 Aug;6(4):456-7   [PMID:  17669900 ]
Interact Cardiovasc Thorac Surg. 2007 Aug;6(4):457   [PMID:  17669903 ]
Interact Cardiovasc Thorac Surg. 2007 Aug;6(4):456; discussion 456   [PMID:  17669902 ]
Interact Cardiovasc Thorac Surg. 2007 Aug;6(4):455; discussion 455   [PMID:  17669898 ]
Interact Cardiovasc Thorac Surg. 2007 Aug;6(4):457   [PMID:  17669904 ]
Interact Cardiovasc Thorac Surg. 2007 Aug;6(4):455; discussion 455   [PMID:  17669899 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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