| Is obesity associated with lower body temperatures? Core temperature: a forgotten variable in energy balance. | |
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MedLine Citation:
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PMID: 19375759 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The global increase in obesity, along with the associated adverse health consequences, has heightened interest in the fundamental causes of excessive weight gain. Attributing obesity to "gluttony and sloth", blaming the obese for overeating and limiting physical activity, oversimplifies a complex problem, since substantial differences in metabolic efficiency between lean and obese have been decisively demonstrated. The underlying physiological basis for these differences have remained poorly understood. The energetic requirements of homeothermy, the maintenance of a constant core temperature in the face of widely divergent external temperatures, accounts for a major portion of daily energy expenditure. Changes in body temperature are associated with significant changes in metabolic rate. These facts raise the interesting possibility that differences in core temperature may play a role in the pathophysiology of obesity. This review explores the hypothesis that lower body temperatures contribute to the enhanced metabolic efficiency of the obese state. |
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Authors:
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Lewis Landsberg; James B Young; William R Leonard; Robert A Linsenmeier; Fred W Turek |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Metabolism: clinical and experimental Volume: 58 ISSN: 1532-8600 ISO Abbreviation: Metab. Clin. Exp. Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-05-18 Completed Date: 2009-06-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375267 Medline TA: Metabolism Country: United States |
Other Details:
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Languages: eng Pagination: 871-6 Citation Subset: IM |
Affiliation:
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Northwestern University Comprehensive Center on Obesity, Chicago, IL 60611, USA. l-landsberg@northwestern.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Basal Metabolism Body Temperature Regulation* Energy Metabolism* Humans Obesity / etiology, physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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