| The nuts and bolts of germ-cell migration. | |
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MedLine Citation:
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PMID: 20947321 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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In many species, primordial germ cells (PGCs) migrate from the position where they are specified to the site where the gonad develops, where they differentiate into sperm and egg. Germ cells thus serve as an excellent model for studying cell migration in the context of the live organism. In recent years, a number of cues directing the migration of the cells towards their target were identified and some of the relevant molecules and biochemical pathways were revealed. In this review we present those results, focusing on 'cell mechanics' of the process including cell adhesion, traction generation and cell polarization. |
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Authors:
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Katsiaryna Tarbashevich; Erez Raz |
Publication Detail:
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Type: Journal Article Date: 2010-10-13 |
Journal Detail:
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Title: Current opinion in cell biology Volume: 22 ISSN: 1879-0410 ISO Abbreviation: Curr. Opin. Cell Biol. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8913428 Medline TA: Curr Opin Cell Biol Country: England |
Other Details:
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Languages: eng Pagination: 715-21 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Institute of Cell Biology, Center for Molecular Biology of Inflammation, Von-Esmarch-Str. 56, 48149, Münster University, 48147 Münster, Germany. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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