Document Detail


A numerical method for cardiac mechanoelectric simulations.
MedLine Citation:
PMID:  19263223     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Much effort has been devoted to developing numerical techniques for solving the equations that describe cardiac electrophysiology, namely the monodomain equations and bidomain equations. Only a limited selection of publications, however, address the development of numerical techniques for mechanoelectric simulations where cardiac electrophysiology is coupled with deformation of cardiac tissue. One problem commonly encountered in mechanoelectric simulations is instability of the coupled numerical scheme. In this study, we develop a stable numerical scheme for mechanoelectric simulations. A number of convergence tests are carried out using this stable technique for simulations where deformations are of the magnitude typically observed in a beating heart. These convergence tests demonstrate that accurate computation of tissue deformation requires a nodal spacing of around 1 mm in the mesh used to calculate tissue deformation. This is a much finer computational grid than has previously been acknowledged, and has implications for the computational efficiency of the resulting numerical scheme.
Authors:
Pras Pathmanathan; Jonathan P Whiteley
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-03-05
Journal Detail:
Title:  Annals of biomedical engineering     Volume:  37     ISSN:  1521-6047     ISO Abbreviation:  Ann Biomed Eng     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-02     Completed Date:  2009-06-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361512     Medline TA:  Ann Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  860-73     Citation Subset:  IM    
Affiliation:
Computing Laboratory, University of Oxford, Wolfson Building, Parks Road, Oxford, OX1 3QD, UK.
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MeSH Terms
Descriptor/Qualifier:
Cardiac Electrophysiology / methods*
Electric Conductivity
Finite Element Analysis
Membrane Potentials
Models, Cardiovascular*
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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