Document Detail

The number of oocytes and the rate of atresia in unilaterally ovariectomized mice up to 8 months after surgery.
MedLine Citation:
PMID:  7431349     Owner:  NLM     Status:  MEDLINE    
Random bred Schofield albino mice were unilaterally ovariectomized or sham-operated at 6 weeks of age and were killed 4, 8, 16 or 32 weeks later. Ovarian weights were recorded before quantitative histological analysis of the total number of oocytes per ovary, the number of follicles per size class, and the proportion of oocytes undergoing atresia. Ovarian weights were consistently higher in the unilaterally ovariectomized mice than in coeval controls and by the 8th week after surgery the weight of the remaining ovary approached the combined weights of the two ovaries in controls. On a per ovary basis, follicular 'pool' size was reduced and the number of growing follicles increased after unilateral ovariectomy, these changes occurring within the first 4 weeks after surgery. Thereafter, oocyte depletion occurred at the control rates. There was no change in the rate of atresia after surgery.
T G Baker; S Challoner; P S Burgoyne
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of reproduction and fertility     Volume:  60     ISSN:  0022-4251     ISO Abbreviation:  J. Reprod. Fertil.     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1981-01-29     Completed Date:  1981-01-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376367     Medline TA:  J Reprod Fertil     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  449-56     Citation Subset:  IM    
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MeSH Terms
Cell Count
Oocytes / pathology*
Organ Size
Ovarian Follicle / pathology
Ovary / pathology*
Ovum / pathology*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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