Document Detail

The number of clonal precursors of the follicular epithelium in the mouse ovary.
MedLine Citation:
PMID:  3184034     Owner:  NLM     Status:  MEDLINE    
The number of clonal precursors of granulosa cells in mouse ovarian follicles has been estimated using a technique based on the phenomenon of random X-chromosome inactivation of somatic cells and the use of an X-linked alloenzyme variant of the glycolytic enzyme PGK-1. The granulosa cells of follicles were oligoclonal in origin and founded by a small number of cells (about 5) which was consistent with histological observations. When the analysis was extended to two subcompartments of the follicle, the mural and cumulus granulosa cells, the results indicated that the cumulus and mural granulosa cells had a common origin.
E Telfer; J D Ansell; H Taylor; R G Gosden
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of reproduction and fertility     Volume:  84     ISSN:  0022-4251     ISO Abbreviation:  J. Reprod. Fertil.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1988-12-22     Completed Date:  1988-12-22     Revised Date:  2010-08-25    
Medline Journal Info:
Nlm Unique ID:  0376367     Medline TA:  J Reprod Fertil     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  105-10     Citation Subset:  IM    
Department of Physiology University Medical School, Edinburgh, U.K.
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MeSH Terms
Cell Differentiation
Clone Cells
Epithelial Cells
Granulosa Cells / cytology,  enzymology
Mice, Inbred Strains
Ovarian Follicle / cytology*
Phosphoglycerate Kinase / metabolism
Grant Support
//Wellcome Trust
Reg. No./Substance:
EC Kinase

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