Document Detail

The nucleolar fibrillar centres in various cell types in vivo or in vitro.
MedLine Citation:
PMID:  991243     Owner:  NLM     Status:  MEDLINE    
Nucleoli were studied in chick fibroblasts cultured in vitro, under normal or under experimental conditions, and in several mammalian cell types in vivo. All these cells frequently contain nucleoli with fibrillar centres. The nucleolar fibrillar centres are composed of fibrous material of low electron density and are always intimately associated with the dense fibrillar component. Their morphology is very similar to that analysed cytochemically in Ehrlich tumour cells. It therefore appears that they could be related to the nucleolar organizers as suggested in Ehrlich tumour cells.
G Goessens
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell and tissue research     Volume:  173     ISSN:  0302-766X     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  1976 Oct 
Date Detail:
Created Date:  1977-01-25     Completed Date:  1977-01-25     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  315-24     Citation Subset:  IM    
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MeSH Terms
Carcinoma, Ehrlich Tumor / ultrastructure
Cell Nucleolus / analysis,  ultrastructure*
Chick Embryo
DNA / analysis
Microscopy, Electron
RNA / biosynthesis
Reg. No./Substance:
63231-63-0/RNA; 9007-49-2/DNA

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