| The nucleation and growth of calcium phosphate crystals at protein and phosphatidylserine liposome surfaces. | |
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MedLine Citation:
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PMID: 9813627 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The kinetics of calcium phosphate crystal growth at the surfaces of proteins and phospholipids has been investigated using free drift and constant composition methods in supersaturated calcium phosphate solutions (relative supersaturations: with respect to hydroxyapatite, HAP, sigma HAP = 15.0, and with respect to octacalcium phosphate, OCP, sigma OCP = 1.9). Fibrinogen and collagen molecules adsorbed at hydrophobic surfaces as well as uncross-linked collagen fibrils induce ion binding and subsequent nucleation of calcium phosphate. The formation of OCP on phosphatidylserine vesicles introduced to highly supersaturated calcium phosphate solutions probably involves the interaction of the calcium ions with the ionized carboxylic groups of the phospholipid. |
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Authors:
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G H Nancollas; A Tsortos; A Zieba |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Scanning microscopy Volume: 10 ISSN: 0891-7035 ISO Abbreviation: Scanning Microsc. Publication Date: 1996 |
Date Detail:
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Created Date: 1998-11-24 Completed Date: 1998-11-24 Revised Date: 2013-04-05 |
Medline Journal Info:
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Nlm Unique ID: 8704616 Medline TA: Scanning Microsc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 499-507; discussion 508 Citation Subset: IM |
Affiliation:
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Department of Chemistry, State University of New York at Buffalo, Amherst, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Calcium Phosphates
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chemistry* Collagen / chemistry Crystallization Fibronectins / chemistry Liposomes / chemistry Microscopy, Electron, Scanning Molecular Conformation Phosphatidylserines / chemistry* |
| Grant Support | |
ID/Acronym/Agency:
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DE03223/DE/NIDCR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Calcium Phosphates; 0/Fibronectins; 0/Liposomes; 0/Phosphatidylserines; 0/alpha-tricalcium phosphate; 0/monocalcium phosphate; 0/tetracalcium phosphate; 9007-34-5/Collagen; 97Z1WI3NDX/calcium phosphate; L11K75P92J/dicalcium phosphate anhydrous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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