| The nuclear autoimmune antigen Ku is also present on the cell surface. | |
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MedLine Citation:
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PMID: 1472635 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Polyclonal antibodies were raised against the individual 85 and 70 kDa subunits of the Ku complex purified from nuclear extract prepared from the T cell line MLA144. They specifically recognise the appropriate subunits of the Ku complex from whole cell extract of HeLa cells using Western blot analysis. They are also able to identify the Ku proteins present in the cell membrane using FACS analysis. |
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Authors:
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R G Dalziel; S C Mendelson; J P Quinn |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Autoimmunity Volume: 13 ISSN: 0891-6934 ISO Abbreviation: Autoimmunity Publication Date: 1992 |
Date Detail:
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Created Date: 1993-02-04 Completed Date: 1993-02-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8900070 Medline TA: Autoimmunity Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 265-7 Citation Subset: IM |
Affiliation:
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Department of Veterinary Pathology, Royal (Dick) School of Veterinary Studies, Summerhall, Edinburgh. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antigens, Nuclear* Autoantigens / analysis* Cell Membrane / metabolism Cell Nucleus / metabolism DNA Helicases* DNA-Binding Proteins / analysis* Flow Cytometry Hela Cells / metabolism Humans Nuclear Proteins / analysis* T-Lymphocytes / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Nuclear; 0/Autoantigens; 0/DNA-Binding Proteins; 0/Ku autoantigen; 0/Nuclear Proteins; 0/XRCC5 protein, human; EC 3.6.1.-/DNA Helicases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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