| A novel way to reduce thrombus build-up in Vena Cava Filters. | |
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MedLine Citation:
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PMID: 21523890 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES AND BACKGROUND: The build-up of thromboses in vena cava filters after deployment presents serious problem to the patients. We proposed a novel way to overcome this problem in a belief that intentionally induced swirling flow can optimize blood flow patterns in Vena cava filters, enhance the stirring motion of flow, in turn accelerate the dissolution of blood clots captured in the filter and facilitate blood to flow pass through the filters. METHODS: In the present study, we experimentally compared the work efficiency of a vena cava filter under swirling flow condition with that of the same filter under normal flow condition. RESULTS: The results show that when compared to the normal flow, the swirling flow indeed has a significantly beneficial effect on a VCF which can decrease its flow-out time nearly 40% and reduce clot build-up in the filter more than 50%. CONCLUSIONS: We therefore believe that the design of an ideal VCF should take how to create swirling flow in the filter into the consideration. © 2011 Wiley-Liss, Inc. |
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Authors:
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Zengsheng Chen; Fan Zhan; Yubo Fan; Xiaoyan Deng |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-26 |
Journal Detail:
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Title: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions Volume: - ISSN: 1522-726X ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100884139 Medline TA: Catheter Cardiovasc Interv Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science & Medical Engineering, Beihang University, Beijing, China, 100191. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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