| A novel three-dimensional tubular scaffold prepared from silk fibroin by electrospinning. | |
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MedLine Citation:
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PMID: 19772871 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Effects of electrospinning parameters (including voltage, collection distance, solution concentration and flow rate) on the morphology and diameter distribution of regenerated SF (silk fibroin) fiber were investigated. Afterward, SF tubular scaffold composed of homogenous fibers was fabricated at voltage of 18kV, collection distance of 18cm, concentration of 37%, and flow rate of 0.15mL/min. After methanol treatment, SF tubular scaffold showed tensile strength of 3.57MPa and porosity of 80.85%. It is satisfied that our work offers a simple method to fabricate seamless and porous tubular scaffold from SF without any additives and organic solvents. Furthermore, the results suggest that this tubular scaffold shows promising applications in small-diameter vascular graft. |
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Authors:
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Juan Zhou; Chuanbao Cao; Xilan Ma |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-09-20 |
Journal Detail:
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Title: International journal of biological macromolecules Volume: 45 ISSN: 1879-0003 ISO Abbreviation: Int. J. Biol. Macromol. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-10-28 Completed Date: 2010-02-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7909578 Medline TA: Int J Biol Macromol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 504-10 Citation Subset: IM |
Affiliation:
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Research Center of Material Science, Beijing Institute of Technology, Beijing 100081, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biocompatible Materials / chemistry Blood Vessel Prosthesis* Bombyx Electrochemistry / methods Extracellular Matrix / metabolism Fibroins / chemistry* Humans Materials Testing Porosity Silk / chemistry* Solvents / chemistry Tensile Strength Tissue Engineering / methods Tissue Scaffolds |
| Chemical | |
Reg. No./Substance:
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0/Biocompatible Materials; 0/Silk; 0/Solvents; 9007-76-5/Fibroins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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