Document Detail

A novel technique of ab interno glaucoma surgery: follow-up results after 24 months.
MedLine Citation:
PMID:  16028025     Owner:  NLM     Status:  MEDLINE    
PURPOSE: It was the aim of this study to investigate the efficacy, longevity, and safety of a new ab interno intervention for the treatment of primary open-angle glaucoma (POAG).
METHODS: The previously described method of radiofrequency-mediated "sclerothalamotomy ab interno" was applied in 53 eyes of consecutive patients with POAG between April 2002 and July 2002. Average preoperative intraocular pressure (IOP) was 25.6+/-2.3 mmHg (range 18-48 mmHg). Sclerothalamotomies were carried out with a custom-made high-frequency dissection 19 G probe (tip 0.3 x 1 mm) applying bipolar current with a frequency of 500 kHz (tip temperature 130 degrees C).
RESULTS: After a follow-up period of 24 months, the average IOP was 15.0+/-1.6 mmHg (range 11-20 mmHg) (p<0.005). The average number of topical agents was 2.6+/-1.0 (range 1-5) preoperatively. Twenty-four months after surgery such agents were used in only five (9.6%) eyes and the average was 0.21+/-0.53 (range 0-2). Transient IOP elevation was observed in 12 of 53 eyes (22.6%) postoperatively. In all cases elevated IOP could efficiently be controlled with topical medication. In general, IOP dropped continuously over the course of the 6 months following surgery and then remained constant.
CONCLUSIONS: This study indicates that sclerothalamotomy ab interno is a safe and efficient surgical method for the treatment of POAG. Long-term results clearly demonstrate the longevity of IOP reduction.
Bojan Pajic; Grigoris Pallas; Heinrich Gerding; Gerding Heinrich; Matthias Böhnke
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Publication Detail:
Type:  Journal Article     Date:  2005-07-19
Journal Detail:
Title:  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie     Volume:  244     ISSN:  0721-832X     ISO Abbreviation:  Graefes Arch. Clin. Exp. Ophthalmol.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-11-30     Completed Date:  2006-03-14     Revised Date:  2011-03-29    
Medline Journal Info:
Nlm Unique ID:  8205248     Medline TA:  Graefes Arch Clin Exp Ophthalmol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  22-7     Citation Subset:  IM    
Department of Ophthalmology, Klinik Pallas, 4600 Olten, Switzerland.
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MeSH Terms
Aged, 80 and over
Anterior Chamber / surgery
Diathermy / methods
Follow-Up Studies
Glaucoma, Open-Angle / physiopathology,  surgery*
Intraocular Pressure / physiology
Middle Aged
Ophthalmologic Surgical Procedures / adverse effects,  methods*
Sclera / surgery
Treatment Outcome
Erratum In:
Graefes Arch Clin Exp Ophthalmol. 2011 Feb;249(2):311
Note: Heinrich, Gerding [corrected to Gerding, Heinrich]

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