Document Detail

A novel study of mechanical heart valve cavitation in a pressurized pulsatile duplicator.
MedLine Citation:
PMID:  19701083     Owner:  NLM     Status:  MEDLINE    
Submission of data regarding the cavitation potential of a mechanical heart valve is recommended by the U.S. Food and Drug Administration in the device-review process. An acoustic method has long been proposed for cavitation detection. However, the question as to whether such a method can differentiate the cavitation noise from the mechanical closing sound has not been sufficiently addressed. In this study, cavitation near a Medtronic Hall tilting disc valve was investigated in a pressurized pulsatile duplicator. The purpose of pressurizing the testing chambers was to prevent cavitation under a normally cavitating loading condition to isolate the mechanical closing sound. By comparing the sound signals before and after pressurization, some noticeable differences were found between them. In the time domain, the intensity of the sound under a cavitating condition was much higher. In the frequency domain, the energy distribution of a sound signal was distinctively different depending on whether cavitation occurred or not. The valve closing sound had a large amount of energy in the low-frequency range (less than about 25 kHz). When cavitation took place, the sound energy shifted toward the high-frequency range (from 25 to 500 kHz).
Changfu Wu; Stephen M Retta; Ronald A Robinson; Bruce A Herman; Laurence W Grossman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  55     ISSN:  1538-943X     ISO Abbreviation:  ASAIO J.     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-09-04     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  445-51     Citation Subset:  IM    
Center for Applied Stochastics Research, Florida Atlantic University, Boca Raton, Florida 33431, USA.
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MeSH Terms
Equipment Failure Analysis / methods
Heart Sounds*
Heart Valve Prosthesis*
Heart Valve Prosthesis Implantation / instrumentation
Materials Testing
Microbubbles / adverse effects*
Pulsatile Flow / physiology*
Grant Support
NSF 03-525//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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