| A novel quantitative method for measuring obstruction in the upper urinary tract: the 'obstruction coefficient'. | |
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MedLine Citation:
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PMID: 18422573 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To define an exact pressure-flow correlation in the upper urinary tract using an improved measurement method, to quantitatively characterize the degree of postrenal obstruction and to find a simple way of calculating it in everyday urological practice. METHODS: The data of 112 cases were included in the analysis. The dynamic method of a multistep, constant pressure perfusion study was used to precisely measure a wide range of pressure-flow dependences. Values of established parameters measuring the degree of obstruction were compared: the intrapelvic pressure, the ureteral opening pressure and the newly introduced 'obstruction coefficient'. RESULTS: Pressure-flow relations can be best presented by a parabolic curve described by the simple formula Y = AX(2) + B. Depending on the degree of obstruction, the shape of this curve can be characterized by a single number, that we defined as the 'obstruction coefficient'. Computer-based evaluation software for the easy calculation of this coefficient is presented here and freely available on demand. The Whitaker-test, the ureteral opening pressure, and the 'obstruction coefficient' showed significant correlation proving that the latter was clinically applicable in measuring the degree of obstruction. CONCLUSION: Calculation of the 'obstruction coefficient' enables us to exactly define the degree of upper urinary tract obstruction and to safely monitor for a long period conditions inhibiting ureteric passage. |
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Authors:
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Sandor Lovasz; Laszlo Lovasz; Peter Nyirady; Imre Romics |
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Publication Detail:
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Type: Journal Article Date: 2008-04-15 |
Journal Detail:
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Title: International journal of urology : official journal of the Japanese Urological Association Volume: 15 ISSN: 1442-2042 ISO Abbreviation: Int. J. Urol. Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-05-20 Completed Date: 2008-08-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9440237 Medline TA: Int J Urol Country: Australia |
Other Details:
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Languages: eng Pagination: 499-504 Citation Subset: IM |
Affiliation:
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Department of Urology, Semmelweis University, Budapest, Hungary. lovasz.sandor@chello.hu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Diagnostic Techniques, Urological Female Humans Male Middle Aged Ureteral Obstruction / diagnosis*, physiopathology Urodynamics* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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