Document Detail

A novel process for recovery and refining of l-lactic acid from fermentation broth.
MedLine Citation:
PMID:  22424924     Owner:  NLM     Status:  Publisher    
This paper introduces a novel process for recovery and refining of l-lactic acid from a fermentation broth. The use of a solvent extraction step, in the novel approach, has significant impacts on the following centrifugal short-path distillation conditions (operating pressure, evaporator temperature and feed flow rate). As the conditions were varied, the l-lactic acid purity and yield in the distillate were monitored. For the purpose of comparison, a series of experiments were also carried out using the existing purification process. The results showed that both of the two processes can obtain l-lactic acid with a high purity around 91.3%, while the yield obtained using the novel process reached 61.73%, which was about 20.43% higher than that using the existing process. Additionally, multiple-pass distillation observed special attention by improving the yield up to 74.63%.
Lijun Chen; Aiwu Zeng; Haibo Dong; Qi Li; Congcong Niu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-3
Journal Detail:
Title:  Bioresource technology     Volume:  -     ISSN:  1873-2976     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9889523     Medline TA:  Bioresour Technol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
State Key Laboratory of Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
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