Document Detail


A novel procedure for the mechanical characterization of the uterine cervix during pregnancy.
MedLine Citation:
PMID:  23274486     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
An in-vivo measurement procedure is presented to characterize the mechanical behavior of human uterine cervix during pregnancy. Based on the aspiration method, a new instrument was developed to provide an inherently safe and easy-to-use mechanical testing technique. Initial measurements were performed on non-pregnant women to develop an appropriate measurement protocol. An inverse analysis was carried out to determine representative model equations for cervical tissue. This model was used in a FE based parametric study focusing on the uncertainties related to the experiment. On this basis, a novel procedure was established which enabled for the first time to conduct mechanical measurements on 50 pregnant women in over 600 applications during gestation. An inverse analysis of the average tissue response at each trimester was performed to determine representative model equations for the cervix in the course of pregnancy.
Authors:
Sabrina Badir; Michael Bajka; Edoardo Mazza
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-11
Journal Detail:
Title:  Journal of the mechanical behavior of biomedical materials     Volume:  -     ISSN:  1878-0180     ISO Abbreviation:  J Mech Behav Biomed Mater     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101322406     Medline TA:  J Mech Behav Biomed Mater     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Departement of Mechanical and Process Engineering, Swiss Federal Institute of Technology Zürich, Tannenstrasse 3, 8092 Zürich, Switzerland. Electronic address: badir@imes.mavt.ethz.ch.
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