| A novel, low cost, disposable, pediatric pulsatile rotary ventricular pump for cardiac surgery that provides a physiological flow pattern. | |
| | |
MedLine Citation:
|
PMID: 18812746 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Research is underway to develop a novel, low cost, disposable pediatric pulsatile rotary ventricular pump (PRVP) for cardiac surgery that provides a physiological flow pattern. This is believed to offer reduced morbidity and risk exposure within this population. The PRVP will have a durable design suitable for use in short- to mid-length prolonged support after surgery without changing pumps. The design is based on proprietary MC3 technology which provides variable pumping volume per stroke, thereby allowing the pump to respond to hemodynamic status changes of the patient. The novel pump design also possesses safety advantages that prevent retrograde flow, and maintain safe circuit pressures upon occlusion of the inlet and outlet tubing. The design is ideal for simple, safe and natural flow support. Computational methods have been developed that predict output for pump chambers of varying geometry. A scaled chamber and pump head (diameter = 4 in) were prototyped to demonstrate target performance for pediatrics (2 L/min at 100 rpm). A novel means of creating a pulsatile flow and pressure output at constant RPM was developed and demonstrated to create significant surplus hydraulic energy (>10%) in a simplified mock patient circuit. |
| | |
Authors:
|
Daniel E Mazur; Kathryn R Osterholzer; John M Toomasian; Scott I Merz |
Related Documents
:
|
18959666 - Investigation of the washout effect in a magnetically driven axial blood pump. 18595366 - Microhaemodynamics within the blade tip clearance of a centrifugal turbodynamic blood p... 2487256 - Preload-responsive, pulsatile-flow, externally valved pump: cardiopulmonary bypass. 3452426 - Development of apparatus for extracorporeal detoxification. 536806 - Survival of red blood cells in rabbits after acute administration of unlabeled stannous... 21631706 - Influence of transfusion technique on survival of autologous red blood cells in the dog. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: ASAIO journal (American Society for Artificial Internal Organs : 1992) Volume: 54 ISSN: 1538-943X ISO Abbreviation: ASAIO J. Publication Date: 2008 Sep-Oct |
Date Detail:
|
Created Date: 2008-09-24 Completed Date: 2008-11-13 Revised Date: 2013-06-05 |
Medline Journal Info:
|
Nlm Unique ID: 9204109 Medline TA: ASAIO J Country: United States |
Other Details:
|
Languages: eng Pagination: 523-8 Citation Subset: IM |
Affiliation:
|
Michigan Critical Care Consultants, Inc, Ann Arbor, Michigan 48103, USA. dmazur@mc3corp.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Flow Velocity Child Equipment Design / economics*, instrumentation Equipment Safety / instrumentation Extracorporeal Circulation / economics*, instrumentation, methods Heart-Assist Devices / economics* Humans Prosthesis Design / economics*, instrumentation Pulsatile Flow / physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
R43 HL085986-01A1/HL/NHLBI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The capability of trapping gaseous microemboli of two pediatric arterial filters with pulsatile and ...
Next Document: A hemodynamic evaluation of the Medos Deltastream DP1 rotary pump and Jostra HL-20 roller pump under...