Document Detail


A novel haemodynamic cerebral aneurysm model of rats with normal blood pressure.
MedLine Citation:
PMID:  22153799     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Cerebral aneurysms of traditional animal models are usually too small to be imaged in vivo. A novel rat model induced by ligation of the unilateral common carotid artery and contralateral pterygopalatine and external carotid arteries was investigatid. To evaluate the morphological changes of the cerebral arteries, synchrotron radiation angiography was utilised at 1month, 2months and 3months after induction. Cerebral aneurysms and expansion of anterior cerebral arteries in these rats were identified when the animals were alive. This novel model is useful for cerebral aneurysm research.
Authors:
Jun Cai; Chuan He; Falei Yuan; Lujia Chen; Feng Ling
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-5
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  -     ISSN:  1532-2653     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Neurosurgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, China; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Avenue, Beijing 100053, China.
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