Document Detail


A novel green gelatin-agar microencapsulation system with P. urinaria as an improved anti-A. niger model.
MedLine Citation:
PMID:  23218379     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In this study, a novel green microencapsulation system was used to develop Phyllanthus urinaria (PU) extract containing microcapsules. Agar was used with gelatin as the wall matrix materials of microcapsules to prevent the use of toxic crosslinker formaldehyde. Microencapsulated PU extract was developed to improve the potential antifungal activities of PU water extracts. The active components and surface morphology of PU extract containing microcapsules were analyzed by liquid chromatography/mass spectrometry and scanning electron microscopy, respectively. The in vitro release study demonstrated that approximately 80% of drug was released after 120h. PU loaded microcapsules were shown to have a stronger anti-Aspergillus niger activity than the free drug.
Authors:
Pik-Ling Lam; Stanton Hon-Lung Kok; Yiu-Wah Ho; Raymond Siu-Ming Wong; Gregory Yin-Ming Cheng; Chor-Hing Cheng; Kim-Hung Lam; Roberto Gambari; Kenneth Ka-Ho Lee; Chung-Hin Chui
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Publication Detail:
Type:  Journal Article     Date:  2012-10-13
Journal Detail:
Title:  Carbohydrate polymers     Volume:  92     ISSN:  1879-1344     ISO Abbreviation:  Carbohydr Polym     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8307156     Medline TA:  Carbohydr Polym     Country:  England    
Other Details:
Languages:  eng     Pagination:  877-80     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Institute of Textiles and Clothing and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China.
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