Document Detail

A novel glucose sensor based on monodispersed Ni/Al layered double hydroxide and chitosan.
MedLine Citation:
PMID:  18782662     Owner:  NLM     Status:  MEDLINE    
A novel cheap and simple amperometric glucose biosensor, based on the electrode modified with the Ni/Al layered double hydroxide (LDH) nanoflakes and chitosan (CHT), without glucose oxidase, is presented. The glucose biosensor based on monodispersed high active Ni/Al-LDH nanoflakes and CHT exhibits an appropriate linear range of 0.01-10mM and good operational stability. The amperometric sensor shows a rapid response at the potential value 0.48V. In addition, optimization of the biosensor construction, the effects of the applied potential, the scan rate as well as common interfering compounds on the amperometric response and human serum samples analysis of the sensor were investigated and discussed.
Hanhua Ai; Xintang Huang; Zhihong Zhu; Jinping Liu; Qingbo Chi; Yuanyuan Li; Zikun Li; Xiaoxu Ji
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-08-05
Journal Detail:
Title:  Biosensors & bioelectronics     Volume:  24     ISSN:  1873-4235     ISO Abbreviation:  Biosens Bioelectron     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-10-20     Completed Date:  2009-02-12     Revised Date:  2009-07-14    
Medline Journal Info:
Nlm Unique ID:  9001289     Medline TA:  Biosens Bioelectron     Country:  England    
Other Details:
Languages:  eng     Pagination:  1054-8     Citation Subset:  IM    
Department of Physics, Central China Normal University, Wuhan 430079, PR China.
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MeSH Terms
Aluminum / chemistry*
Biosensing Techniques / instrumentation*,  methods
Chitosan / chemistry*
Coated Materials, Biocompatible / chemistry
Electrochemistry / instrumentation*
Equipment Design
Equipment Failure Analysis
Glucose / analysis*
Glucose Oxidase / chemistry*
Hydroxides / chemistry
Nanoparticles / chemistry
Nickel / chemistry*
Reproducibility of Results
Sensitivity and Specificity
Reg. No./Substance:
0/Coated Materials, Biocompatible; 0/Hydroxides; 50-99-7/Glucose; 7429-90-5/Aluminum; 7440-02-0/Nickel; 9012-76-4/Chitosan; EC Oxidase

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