| The novel gluconeogenesis inhibitor FR225654 that originates from Phoma sp. no. 00144. III. Structure determination. | |
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MedLine Citation:
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PMID: 16161488 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A novel gluconeogenesis inhibitor, FR225654 was isolated from the culture broth of Phoma sp. No. 00144. Spectroscopic analysis concluded that FR225654 has a highly oxygenated trans-decalin ring and beta-keto-enol in its main part, and has a characteristic side chain possessing a conjugated carboxylic acid and tri-substituted olefin. |
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Authors:
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Yoshihiro Ohtsu; Seiji Yoshimura; Takayoshi Kinoshita; Shigehiro Takase; Hidenori Nakajima |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of antibiotics Volume: 58 ISSN: 0021-8820 ISO Abbreviation: J. Antibiot. Publication Date: 2005 Jul |
Date Detail:
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Created Date: 2005-09-15 Completed Date: 2005-09-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0151115 Medline TA: J Antibiot (Tokyo) Country: Japan |
Other Details:
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Languages: eng Pagination: 479-82 Citation Subset: IM |
Affiliation:
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Fermentation Research Laboratories, Fujisawa Pharmaceutical Co, Ltd. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Gluconeogenesis
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drug effects Hypoglycemic Agents / chemistry*, isolation & purification, pharmacology Molecular Structure Naphthalenes / chemistry*, isolation & purification, pharmacology Stereoisomerism Structure-Activity Relationship |
| Chemical | |
Reg. No./Substance:
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0/FR225654; 0/Hypoglycemic Agents; 0/Naphthalenes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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