| A novel family of linear plasmids with homology to plasmid pAL2-1 of Podospora anserina. | |
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MedLine Citation:
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PMID: 7700237 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three recently isolated wild-type strains of the ascomycete Podospora anserina were analyzed for the presence of linear mitochondrial plasmids. In one of these strains, designated Wat, at least 12 distinct plasmid-like elements were identified. From molecular analyses a minimum number of 78 individual linear molecules with proteins bound to their 5' ends was estimated. In addition, the different members of this family of typical linear plasmids were shown to possess a common central region and terminal sequences which differ from one plasmid to another due to the presence of different numbers of a 2.4 kb sequence module. Finally, the pWa6 plasmids share a high degree of sequence similarity with pAL2-1, a linear plasmid previously identified in mitochondria of a long-lived mutant of P.anserina. A mechanism is proposed which explains the generation of these distinct, closely related extra-chromosomal genetic traits. |
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Authors:
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J Hermanns; F Debets; R Hoekstra; H D Osiewacz |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Molecular & general genetics : MGG Volume: 246 ISSN: 0026-8925 ISO Abbreviation: Mol. Gen. Genet. Publication Date: 1995 Mar |
Date Detail:
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Created Date: 1995-05-01 Completed Date: 1995-05-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0125036 Medline TA: Mol Gen Genet Country: GERMANY |
Other Details:
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Languages: eng Pagination: 638-47 Citation Subset: IM |
Affiliation:
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German Cancer Research Center, Department of Molecular Biology of Aging Processes, Heidelberg. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Ascomycota
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genetics* Base Sequence DNA Replication / genetics DNA, Fungal / analysis, genetics* DNA, Mitochondrial / analysis, genetics* Exodeoxyribonucleases Models, Genetic Molecular Sequence Data Nucleic Acid Conformation Plasmids / chemistry, genetics* Sequence Homology, Nucleic Acid* |
| Chemical | |
Reg. No./Substance:
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0/DNA, Fungal; 0/DNA, Mitochondrial; EC 3.1.-/Exodeoxyribonucleases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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