Document Detail

A novel experimental system for investigation of cortical activities related to lower limb movements.
MedLine Citation:
PMID:  17946974     Owner:  NLM     Status:  MEDLINE    
We report the development of a novel experimental system for investigation of potential correlation between cortical neuronal signals and lower limb movement with targeted application towards cortical controlled neuroprosthesis. The system consists of a specially designed chair and a virtual reality based task environment. We designed a training paradigm for non-human primates to perform whole leg full extension and retraction task that simulates standing and sitting. With the special chair, the 'stand up' and 'sit down' can be performed with the head fixed, which is required for steady and especially acute cortical recordings. In this experimental environment we can simultaneously record leg kinematics during simulated stand up and stepping, ground reaction forces, leg muscle activities and neuronal activities in different cortical areas through either microdriveable electrodes or chronically implanted arrays. With this system and other state-of-the-art techniques, and combined with computational tools that we are developing, we aim to identify neural activity patterns that correlate with muscle activity and/or kinematics associated with leg movement during standing and stepping activities under naive and well trained conditions.
Chaolin Ma; Jiping He
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  1     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2006  
Date Detail:
Created Date:  2007-10-23     Completed Date:  2008-03-13     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2679-82     Citation Subset:  IM    
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MeSH Terms
Brain Mapping / instrumentation*,  methods
Equipment Design
Equipment Failure Analysis
Evoked Potentials, Motor / physiology*
Lower Extremity / physiology*
Motor Cortex / physiology*
Movement / physiology*
Restraint, Physical / instrumentation*,  methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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