| A novel experimental method to estimate stress-strain behavior of intact coronary arteries using intravascular ultrasound (IVUS). | |
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MedLine Citation:
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PMID: 12661205 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most arterial mechanics studies have focused on excised non-coronary vessels, with few studies validating the application of ex-vivo results to in-vivo conditions. A method was developed for testing the mechanical properties of intact left anterior descending coronary arteries under a variety of conditions. Vascular deformation and pressure were simultaneously measured with intravascular ultrasound and a pressure transducer guidewire, respectively. Results suggest the importance of understanding in-vivo factors such as myocardial support, vascular tone and local pressure fluctuations when applying ex-vivo coronary characterization data. With further development, this method can more accurately characterize the true in-vivo constitutive behavior in normal and atherosclerotic coronaries. |
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Authors:
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Azita Tajaddini; Deborah L Kilpatrick; D Geoffrey Vince |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Validation Studies |
Journal Detail:
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Title: Journal of biomechanical engineering Volume: 125 ISSN: 0148-0731 ISO Abbreviation: J Biomech Eng Publication Date: 2003 Feb |
Date Detail:
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Created Date: 2003-03-28 Completed Date: 2003-09-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7909584 Medline TA: J Biomech Eng Country: United States |
Other Details:
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Languages: eng Pagination: 120-3 Citation Subset: IM |
Affiliation:
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Department of Biomedical Engineering/ND20 Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA. tajadda@bme.ri.ccf.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Arteries / physiopathology, ultrasonography Coronary Restenosis / physiopathology*, ultrasonography* Coronary Vessels / physiopathology*, ultrasonography* Elasticity Feasibility Studies Humans Motion Reproducibility of Results Sensitivity and Specificity Stress, Mechanical Swine Ultrasonography, Interventional / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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