| A novel copper(II) mononuclear complex with the non-steroidal anti-inflammatory drug diclofenac: Structural characterization and biological activity. | |
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MedLine Citation:
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PMID: 23280425 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A copper(II) complex with the non-steroidal anti-inflammatory drug (NSAID) diclofenac has been for the first time synthesized and characterized without any co-organic ligand. Its biological activity against four human cell lines underlined a higher activity of the monomeric complex than the parent molecule in the case of tumoral cell lines. A ternary Cu-diclofenac-albumin complex was suspected to be the reactive species in biological medium. |
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Authors:
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Stéphanie Sayen; Annie Carlier; Michel Tarpin; Emmanuel Guillon |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-16 |
Journal Detail:
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Title: Journal of inorganic biochemistry Volume: 120C ISSN: 1873-3344 ISO Abbreviation: J. Inorg. Biochem. Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2013-1-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7905788 Medline TA: J Inorg Biochem Country: - |
Other Details:
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Languages: ENG Pagination: 39-43 Citation Subset: - |
Copyright Information:
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Copyright © 2012. Published by Elsevier Inc. |
Affiliation:
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Institut de Chimie Moléculaire de Reims (ICMR, UMR CNRS 7312), Groupe Chimie de Coordination, Université de Reims Champagne-Ardenne, F-51687 Reims Cedex 2, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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