| A novel bronchial artery catheterization technique with preserved blood flow in an ovine model. | |
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MedLine Citation:
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PMID: 20334606 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors devised a novel bronchial artery catheterization technique to deliver agents directly into bronchial circulation with preserved blood flow in an awake ovine model. A polyurethane catheter was inserted into bronchial artery via an incision into the 4th intercostal space. Regional blood flow of the airway was measured by fluorescent microspheres before cannulation, after cannulation, and 7 days after the operative procedure. The blood flows were also measured in a sham group (no cannulation, no ligation, n = 6), cannulation group (bronchial artery cannulation, n = 5), and ligation group (bronchial artery ligation, n = 5) at baseline and 6 hours after burn and smoke inhalation injury. The regional blood flows decreased slightly after cannulation in proximal bronchi, but recovered after 7 days. The regional blood flow increased 10-fold after inhalation injury in bronchi of the sham group. Bronchial artery ligation significantly attenuated the increase of blood flow. However, cannulation preserved regional blood flow and did not prevent the blood flow increases after burn and smoke inhalation injury, thus constituting a novel bronchial artery catheterization technique. |
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Authors:
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Atsumori Hamahata; Perenlei Enkhbaatar; Sakurai Hiroyuki; Naoki Morita; Yoshimitsu Nakano; Matthias Lange; Motohiro Nozaki; Lillian D Traber; Daniel L Traber |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Experimental lung research Volume: 36 ISSN: 1521-0499 ISO Abbreviation: Exp. Lung Res. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-25 Completed Date: 2010-06-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8004944 Medline TA: Exp Lung Res Country: England |
Other Details:
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Languages: eng Pagination: 183-9 Citation Subset: IM |
Affiliation:
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Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bronchial Arteries / physiopathology*, surgery Burns / physiopathology Catheterization / methods* Disease Models, Animal Female Ligation Lung / blood supply* Pulmonary Circulation* Regional Blood Flow Sheep Smoke Inhalation Injury / physiopathology Time Factors Wakefulness |
| Grant Support | |
ID/Acronym/Agency:
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GM060688/GM/NIGMS NIH HHS; GM66312/GM/NIGMS NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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