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A novel bio-electrochemical ascorbic acid sensor modified with Cu(4)(OH)(6)SO(4) nanorods.
MedLine Citation:
PMID:  20949190     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Cu(4)(OH)(6)SO(4) (brochantite) is an undesirable oxidation product of copper-bearing sulfides, and it is seldom considered to be biologically and electrochemically active. In this paper, we report that Cu(4)(OH)(6)SO(4) nanoparticles in fact possess an intrinsic electrocatalytic activity, which is explored as a biosensing material to oxidize l-ascorbic acid (AA). The Cu(4)(OH)(6)SO(4) nanorod modified biosensor exhibits excellent performance for the determination of l-ascorbic acid with a response time of less than 8 s, a linear range between 0.017 and 6 mM, and a sensitivity of 17.53 μA mM(-1). A high selectivity towards the oxidation of AA in the presence of dopamine (DA) and acetyl aminophenol (AP) is also observed at their maximum physiological concentrations. The good analytical performance and long-term stability, low cost and straightforward fabrication method made the Cu(4)(OH)(6)SO(4) nanomaterials promising for the development of effective electrochemical sensors for a wide range of potential applications in medicine, biotechnology and environmental chemistry.
Authors:
Cao Xia; Wang Ning
Publication Detail:
Type:  Journal Article     Date:  2010-10-14
Journal Detail:
Title:  The Analyst     Volume:  136     ISSN:  1364-5528     ISO Abbreviation:  Analyst     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372652     Medline TA:  Analyst     Country:  England    
Other Details:
Languages:  eng     Pagination:  288-92     Citation Subset:  IM    
Affiliation:
School of Material Science and Engineering, Jiangsu University of Science and Technology, Jiangsu, 212003, China.
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