| A novel approach to chronic total occlusions: the crosser system. | |
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MedLine Citation:
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PMID: 16764006 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To evaluate safety and efficacy of the CROSSER CTO Recanalization System (CROSSER). BACKGROUND: The CROSSER, a novel device dedicated to recanalization of chronic total occlusions (CTO), relies on a monorail catheter delivering vibrational energy to facilitate the crossing of occluded coronary arteries. METHODS: We included de novo or restenotic occlusions in native coronary arteries with typically unfavorable characteristics and a prior failed guidewire attempt either performed in a previous procedure or just before the usage of the CROSSER. The end points analyzed were technical success (ability to cross or facilitate a guidewire crossing into the true lumen), angiographic success (<20% residual stenosis and TIMI flow grade 3), and clinical success (angiographic success and freedom from major adverse cardiac events at 30 days). RESULTS: Twenty-eight patients (30 lesions) were included. The morphology was blunt in 83.3% and the length of the occlusion was >20 mm in 76.6%. The median age of the CTO was 9 months (range 3-60 months). Technical success was obtained in 19 (63%) occlusions and angiographic success in 16 (53%): 26.3% in lesions with prior procedural failure and 73.7% when CROSSER was attempted after initial guidewire failure. Complications were: one guidewire perforation without consequences and one peri-procedural myocardial infarction (MI). No events occurred within 30-day follow-up after discharge. CONCLUSIONS: In our experience, the CROSSER System is safe and increases the success of opening CTO refractory to guidewires. This novel device may represent an useful adjunct to the armamentarium of the interventional cardiologist. |
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Authors:
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Gloria Melzi; John Cosgrave; Giuseppe L Biondi-Zoccai; Flavio Airoldi; Iassen Michev; Alaide Chieffo; Giuseppe M Sangiorgi; Matteo Montorfano; Mauro Carlino; Antonio Colombo |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions Volume: 68 ISSN: 1522-1946 ISO Abbreviation: Catheter Cardiovasc Interv Publication Date: 2006 Jul |
Date Detail:
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Created Date: 2006-06-28 Completed Date: 2006-12-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100884139 Medline TA: Catheter Cardiovasc Interv Country: United States |
Other Details:
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Languages: eng Pagination: 29-35 Citation Subset: IM |
Copyright Information:
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Copyright 2006 Wiley-Liss, Inc. |
Affiliation:
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EMO Centro Cuore Columbus, Milan, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Chronic Disease Coronary Angiography Coronary Circulation Coronary Disease / physiopathology, radiography, therapy* Equipment Design Female Heart Catheterization / instrumentation* Humans Male Middle Aged Treatment Outcome Vibration / therapeutic use* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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