Document Detail

A nonrandomized comparison of potassium titanyl phosphate and CO2 laser fiber stapedotomy for primary otosclerosis with the otology-neurotology database.
MedLine Citation:
PMID:  20058319     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES/HYPOTHESIS: To compare short-term hearing results in patients undergoing laser stapedotomy for primary otosclerosis using either the flexible potassium titanyl phosphate (KTP) or CO(2) laser fiber. STUDY DESIGN: Prospective nonrandomized clinical study at a tertiary referral center. METHODS: Two hundred fourteen patients undergoing 214 stapedotomies for otosclerotic stapes fixation were enrolled in this study from January 2008 to January 2010. Comparative analyses were made between a group of 107 patients who underwent stapedotomy with the flexible KTP laser fiber and 107 patients who underwent stapedotomy with the flexible CO(2) laser fiber. Preoperative and postoperative audiometric evaluation at 3 months using conventional audiometry, namely, air-bone gap (ABG), bone-conduction thresholds, and air-conduction thresholds, were assessed. RESULTS: In the KTP laser group the postoperative ABG was 4.3 dB compared to 3 dB in the CO(2) group, which is a mean difference of 1.3 dB (95% confidence interval [CI], -0.3 to 2.8; P = .10). Of the patients from the KTP group, 92% had a postoperative ABG of 10 dB or less, as compared to 97% in the CO(2) group (mean difference 5%; 95% CI, -10 to 1; P = .14). The postoperative ABG at 4 kHz was 4.9 dB in the KTP and 2.2 dB in the CO(2) group, which is a mean difference of 2.7 dB (95% CI, 0.6-4.7, P = .01). No sensorineural hearing loss was reported. CONCLUSIONS: The use of the CO(2) laser fiber appears to be associated with slightly better hearing results than the KTP laser fiber, especially when assessed at the 4 kHz frequency.
Robert Vincent; Wilko Grolman; John Oates; Neil Sperling; Maroeska Rovers
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Laryngoscope     Volume:  120     ISSN:  1531-4995     ISO Abbreviation:  Laryngoscope     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-26     Completed Date:  2010-04-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  United States    
Other Details:
Languages:  eng     Pagination:  570-5     Citation Subset:  IM    
Jean Causse Ear Clinic, Traverse de B?ziers, Colombiers, France.
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MeSH Terms
Chi-Square Distribution
Laser Therapy / instrumentation*
Lasers, Gas*
Linear Models
Middle Aged
Otosclerosis / surgery*
Prospective Studies
Stapes Surgery / instrumentation*
Treatment Outcome
Reg. No./Substance:
0/Phosphates; 12690-20-9/potassium titanylphosphate; 7440-32-6/Titanium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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