Document Detail


The non-invasive determination of cardiac output in children: a three-breath technique.
MedLine Citation:
PMID:  3136684     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study, the cardiac output of 11 children (5 days to 18 yr of age) was measured following cardiopulmonary bypass. Standard dye dilution cardiac outputs and an indirect Fick-CO2 technique were simultaneously determined. A rebreathing maneuver is described to estimate the oxygenated mixed venous PCO2 (PvCO2). This estimate of PvCO2 was combined with the end tidal PCO2 and CO2 production to give a non-invasive Fick estimate of the cardiac output. Non-invasive cardiac outputs correlated well with those measured by dye-dilution (r2 = 0.94) over a range of cardiac outputs from 490-7280 ml/min. All non-invasive determinations were within 15% of the line of identity, and within 22% of averaged replicate dye-dilution values. Our results agree with previous comparisons of indirect Fick-CO2 methods with invasive determinations of cardiac output. These data suggest that the indirect Fick-CO2 technique offers a rapid, non-invasive alternative to invasive monitoring of cardiac output.
Authors:
W D Morton
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesiology     Volume:  69     ISSN:  0003-3022     ISO Abbreviation:  Anesthesiology     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1988-09-22     Completed Date:  1988-09-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1300217     Medline TA:  Anesthesiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  223-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Anesthesia, Hospital for Sick Children, Toronto, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Carbon Dioxide / blood*,  metabolism
Cardiac Output*
Child
Child, Preschool
Dye Dilution Technique
Forced Expiratory Flow Rates
Humans
Infant
Infant, Newborn
Oxygen / blood
Respiration
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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