Document Detail


Is non-alcoholic steatohepatitis a predisposing factor to porphyria cutanea tarda?
MedLine Citation:
PMID:  23458397     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Porphyria cutanea tarda (PCT) is a disease caused by a deficiency of the fifth enzyme of the heme biosynthetic pathway in the liver that manifests in the skin as blistering and fragility of predominantly sun-exposed skin. It occurs in individuals with environmental and/or genetic risk factors such as estrogen use, hepatitis C infection and hemochromatosis gene mutations. This report highlights a case of PCT which manifested in an individual with non-alcoholic fatty liver disease (non-alcoholic steatohepatitis; NASH). We propose that NASH may have been a contributing factor for the development of PCT in our patient.
Authors:
Elizabeth N Ergen; Elizabeth Seidler; Samir Parekh; Sareeta R S Parker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Photodermatology, photoimmunology & photomedicine     Volume:  29     ISSN:  1600-0781     ISO Abbreviation:  Photodermatol Photoimmunol Photomed     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013641     Medline TA:  Photodermatol Photoimmunol Photomed     Country:  England    
Other Details:
Languages:  eng     Pagination:  106-8     Citation Subset:  IM    
Copyright Information:
© 2013 John Wiley & Sons A/S.
Affiliation:
Vanderbilt University Medical Center, Nashville, TN, USA.
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