| The no-reflow phenomenon in the coronary circulation. | |
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MedLine Citation:
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PMID: 19689256 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The no-reflow phenomenon is a poorly understood complication of percutaneous coronary intervention in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion from the epicardial coronary artery or arteries. In this contemporary review we endeavour to discuss the pathophysiology of coronary no-reflow, understand the predictors and describe current pharmacological and mechanical strategies to prevent and treat coronary no-reflow. |
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Authors:
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Thomas J Kiernan; Nicholas J Ruggiero; Juan M Bernal; Creighton W Don; Christian Witzke; Gareth D Kiernan; Roberto J Cubeddu; Bryan P Yan |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Cardiovascular & hematological agents in medicinal chemistry Volume: 7 ISSN: 1875-6182 ISO Abbreviation: - Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-08-19 Completed Date: 2009-10-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101266881 Medline TA: Cardiovasc Hematol Agents Med Chem Country: Netherlands |
Other Details:
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Languages: eng Pagination: 181-92 Citation Subset: IM |
Affiliation:
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Division of Interventional Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. tjkiernan@partners.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine
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therapeutic use Animals Coronary Circulation* Diltiazem / therapeutic use Humans Nicardipine / therapeutic use Nicorandil / therapeutic use Nitroprusside / therapeutic use No-Reflow Phenomenon / drug therapy*, physiopathology*, therapy Prostheses and Implants Vasodilator Agents / therapeutic use Verapamil / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Vasodilator Agents; 15078-28-1/Nitroprusside; 42399-41-7/Diltiazem; 52-53-9/Verapamil; 55985-32-5/Nicardipine; 58-61-7/Adenosine; 65141-46-0/Nicorandil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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