Document Detail

A newly designed amplatz sheath decreases intrapelvic irrigation pressure during mini-percutaneous nephrolitholapaxy: an in-vitro pressure-measurement and microscopic study.
MedLine Citation:
PMID:  17941796     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: In recent years, mini-percutaneous nephrolitholapaxy (mini-PCNL) has gained popularity because of its reduced invasiveness. To improve clinical outcomes further, research is ongoing in selected centers. Important areas of interest include extravasation into the retroperitoneal space, acute absorption syndrome, and septicemia. The aim of this experimental study was to test a new 18F nephroscope sheath specially designed to decrease intrapelvic pressure during mini-PCNL whatever the irrigation pressure. In addition, the hydrodynamic effects of this device can be used for suction and removal of the stone fragments, in contrast to a standard Amplatz sheath. MATERIALS AND METHODS: In a fresh, perfused cadaveric porcine kidney model, the new sheath was compared with a conventional sheath (control) with closed and open Luer-Lok outflow under increasing irrigation pressure. Intrarenal pressure peaks were measured with a urodynamic workstation. The irrigation fluid was marked with an ink that stains only endoluminal surfaces, and a post-measurement histopathologic work-up was performed to evaluate the changes on a morphologic level. RESULTS: Closing of the control sheath resulted in an increase in the intrapelvic pressure to a maximum of 136 cm H2O. Using the new sheath with a constant output flow made possible by its open proximal end, the maximal intrapelvic pressure remained low at 20 cm H2O, even when the inflow pressure reached 125 cm H2O. The ink distribution on the hematoxylin and eosin-stained slides reflected the results of the pressure measurements. CONCLUSIONS: Newly designed nephroscope sheaths with an open proximal end, such as the one described here, decrease the intrapelvic pressure compared with a closed outflow system. As a result, strict fluid control during the intervention is not necessary.
Udo Nagele; Marcus Horstmann; Karl-Dietrich Sievert; Markus A Kuczyk; Ute Walcher; Jörg Hennenlotter; Arnulf Stenzl; Aristotelis G Anastasiadis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of endourology / Endourological Society     Volume:  21     ISSN:  0892-7790     ISO Abbreviation:  J. Endourol.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-10-18     Completed Date:  2008-01-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807503     Medline TA:  J Endourol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1113-6     Citation Subset:  IM    
Department of Urology, University of Tuebingen, Tuebingen, Germany.
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MeSH Terms
Equipment Design
Fluorine Radioisotopes / chemistry
Irrigation / instrumentation*,  methods*
Kidney / metabolism
Microscopy / methods
Nephrostomy, Percutaneous / instrumentation*,  methods*
Treatment Outcome
Urologic Surgical Procedures / instrumentation*,  methods
Water / chemistry
Reg. No./Substance:
0/Fluorine Radioisotopes; 7732-18-5/Water

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