| A new and weakly antispasmodic protoberberine alkaloid from Rhizoma Coptidis. | |
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MedLine Citation:
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PMID: 20564546 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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A new protoberberine alkaloid, 3-hydroxy-2-methoxy-9,10-methylenedioxy-8-oxo-protoberberine, along with three known compounds, was isolated from Rhizoma Coptidis. The new compound displayed weak antispasmodic activity against acetylcholine-induced contraction in isolated guinea-pig ileum with an IC50 of 83.7 microm. |
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Authors:
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Ming Zhao; Yan-Fang Xian; Siu-Po Ip; Harry Hs Fong; Chun-Tao Che |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Phytotherapy research : PTR Volume: 24 ISSN: 1099-1573 ISO Abbreviation: Phytother Res Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8904486 Medline TA: Phytother Res Country: England |
Other Details:
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Languages: eng Pagination: 1414-6 Citation Subset: IM |
Copyright Information:
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Copyright 2010 John Wiley & Sons, Ltd. |
Affiliation:
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School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong. |
Export Citation:
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Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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U19 AT003266/AT/NCCAM NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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