Document Detail

A new variant of Brucella melitensis.
MedLine Citation:
PMID:  16700714     Owner:  NLM     Status:  MEDLINE    
Brucella melitensis is highly pathogenic and constitutes a serious risk to public health. In Argentina, biovar 1 has been isolated from infected animals, but the Rev.1 strain vaccine is not authorised for use. This report describes nine atypical B. melitensis isolates obtained from humans. These isolates grew slowly, produced small colonies and were susceptible to penicillin and dyes, similar to the B. melitensis Rev.1 vaccine strain, but were inhibited by streptomycin 2.5 mg/L. The isolation of such atypical B. melitensis variants has never been reported from animals in Argentina, and could indicate the emergence of a new mutant variant.
N E Lucero; S M Ayala; G I Escobar; M Grayon; I Jacques
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases     Volume:  12     ISSN:  1198-743X     ISO Abbreviation:  Clin. Microbiol. Infect.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-16     Completed Date:  2007-10-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9516420     Medline TA:  Clin Microbiol Infect     Country:  France    
Other Details:
Languages:  eng     Pagination:  593-6     Citation Subset:  IM    
Brucellosis Laboratory, Administración Nacional de Laboratorios e Institutos de Salud Dr C.G. Malbrán, ANLIS, Buenos Aires, Argentina.
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MeSH Terms
Bacterial Typing Techniques / methods
Brucella melitensis / classification*,  drug effects,  genetics,  isolation & purification*
Brucellosis / microbiology*
Child, Preschool
Microbial Sensitivity Tests
Penicillins / pharmacology
Polymerase Chain Reaction / methods
Polymorphism, Restriction Fragment Length
Reg. No./Substance:

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