| A new triterpenoid from Verbena officinalis L. | |
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MedLine Citation:
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PMID: 23061751 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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To investigate the chemical constituents of Verbena officinalis L., five triterpenoid constituents were isolated and elucidated as 3α,19,23-trihydroxyurs-12-en-28-oic acid, namely, 4-epi-barbinervic acid (1), 2α,3β-dihydroxyurs-12-en-28-oic acid (2), 3α,24-dihydroxyurs-12-en- 28-oic acid (3), 3α,24-dihydroxy-olean-12-en-28-oic acid (4), ursolic acid (5), using spectroscopic methods and comparing with published data. Compounds 2 and 4 were obtained from V. officinalis for the first time, and compound 1 is a new triterpenoid compound, which exhibits significantly higher antitumor activity against human hepatoma cell line Bel 7402 in vitro than the blank control. |
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Authors:
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Ji-Cheng Shu; Jian-Qun Liu; Gui-Xin Chou |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-15 |
Journal Detail:
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Title: Natural product research Volume: - ISSN: 1478-6427 ISO Abbreviation: Nat. Prod. Res. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101167924 Medline TA: Nat Prod Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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a The MOE Key Laboratory for Standardization of Chinese Medicines , Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine , Shanghai 201203 , China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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