Document Detail

A new subhaplogroup of native American Y-Chromosomes from the Andes.
MedLine Citation:
PMID:  21913173     Owner:  NLM     Status:  Publisher    
The human Y chromosome contains highly informative markers for making historical inferences about the pre-Columbian peopling of Americas. However, the scarcity of these markers has limited its use in the inference of shared ancestry and past migrations relevant to the origin of the culturally and biologically diverse Native Americans. To identify new single nucleotide polymorphisms (SNPs) and increase the phylogenetic resolution of the major haplogroup Q found in the Americas, we have performed a search for new polymorphisms based on sequencing divergent Y chromosomes identified by microsatellite haplotype analysis. Using this approach, a new Y-SNP (SA01) has been identified in the Andean populations of South America, allowing for the detection of a new sublineage of Q1a3a. This sublineage displays a less complex phylogeographic network of associated microsatellites and more restricted geographic occurrence, and is given the designation Q1a3a4. This result indicates that our approach can be successfully used to identify sublineages of interest in a specific region that allow the investigation of particular histories of human populations. Am J Phys Anthropol 2011. © 2011 Wiley-Liss, Inc.
Marilza S Jota; Daniela R Lacerda; José R Sandoval; Pedro Paulo R Vieira; Simone S Santos-Lopes; Rafael Bisso-Machado; Vanessa R Paixão-Cortes; Susana Revollo; Cesar Paz-Y-Miño; Ricardo Fujita; Francisco M Salzano; Sandro L Bonatto; Maria Cátira Bortolini; Fabrício R Santos;
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-13
Journal Detail:
Title:  American journal of physical anthropology     Volume:  -     ISSN:  1096-8644     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400654     Medline TA:  Am J Phys Anthropol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
Departamento de Biologia Geral, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
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