| A new strategy for the reduction of acute myocardial infarction in variant angina. | |
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MedLine Citation:
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PMID: 1835559 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To study the effects of stepwise early treatment in variant angina pectoris, frequencies of cardiac events and complications were examined after three different types of treatment. The subjects of the study consisted of 159 consecutive patients with variant angina pectoris, who were in need of hospitalization. The three treatment modalities were the introduction of calcium antagonists, nicorandil and nitroglycerin infusion, and percutaneous transluminal coronary angioplasty (PTCA), respectively. The cardiac event rate for this series of patients was 16% (25 of 159). The cumulative cardiac event rate was 22% at 1 year and 23% at 3 years in the first treatment period; 11% at the same intervals in the second treatment period; and 6% at the same intervals in the third treatment period. Our results suggest that it is important in the treatment of variant angina pectoris not only to prevent anginal attacks by the use of fast-acting coronary vasodilators, but also to initiate early revascularization. |
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Authors:
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H Kishida; Y Tada; Y Tetsuoh; Y Yamazaki; T Saito; N Fukuma; N Hata; M Yasutake; H Hayakawa |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American heart journal Volume: 122 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1991 Dec |
Date Detail:
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Created Date: 1991-12-31 Completed Date: 1991-12-31 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1554-61 Citation Subset: AIM; IM |
Affiliation:
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Department of Internal Medicine, Nippon Medical School, Tokyo, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angina Pectoris, Variant / complications*, epidemiology, therapy Angioplasty, Transluminal, Percutaneous Coronary Calcium Channel Blockers / therapeutic use Coronary Angiography Drug Therapy, Combination Evaluation Studies as Topic Female Humans Male Middle Aged Myocardial Infarction / epidemiology, etiology, prevention & control* Niacinamide / administration & dosage, analogs & derivatives Nicorandil Nitroglycerin / administration & dosage Regression Analysis Retrospective Studies Vasodilator Agents / administration & dosage |
| Chemical | |
Reg. No./Substance:
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0/Calcium Channel Blockers; 0/Vasodilator Agents; 55-63-0/Nitroglycerin; 65141-46-0/Nicorandil; 98-92-0/Niacinamide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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