| A new strategy for the preparation of supramolecular neutral hydrogels. | |
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MedLine Citation:
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PMID: 11888311 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This paper demonstrates that miscible blends from water-insoluble polymers, such as poly(2,4,4-trimethylhexamethylene terephthalamide) (1), methylamine imidized poly(methyl methacrylate) (2), and aromatic poly(ether sulfone) (3) and water-soluble polymers, such as poly(2-ethyl-2-oxazoline) (4) and poly(N-vinyl pyrrolidone) (5), respectively, represent a new class of supramolecular hydrogels. When the degree of polymerization (DP) of the water-soluble polymer is larger than that of water-insoluble polymer, the resulting hydrogels adsorb extremely high amounts of water (i.e., 229 wt % in the case of the hydrogel 1/4) and remain mechanically tough. The high water uptake capability of these blends is explained by a supramolecular network structure generated by H-bonding and/or other noncovalent interactions between the water-insoluble hydrophobic polymer and water-soluble hydrophilic segments as reversible cross-linking points interconnected by hydrophilic water soluble segments. The glass transition temperatures of these hydrogels are tailored via the ratio between the weight percent of the two polymers and by the glass transition temperature of the parent polymers. These supramolecular hydrogels can be processed from melt or solution and maintain excellent mechanical properties both in dry and in the water swollen state. This class of hydrogels is of interest for areas such as membranes, contact lenses, tissue engineering, and other biomedical applications. |
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Authors:
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Virgil Percec; Tushar K Bera; Robert J Butera |
Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Biomacromolecules Volume: 3 ISSN: 1525-7797 ISO Abbreviation: Biomacromolecules Publication Date: 2002 Mar-Apr |
Date Detail:
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Created Date: 2002-03-12 Completed Date: 2002-07-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100892849 Medline TA: Biomacromolecules Country: United States |
Other Details:
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Languages: eng Pagination: 272-9 Citation Subset: IM |
Affiliation:
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DuPont Performance Coatings, Marshall Laboratory, Philadelphia, Pennsylvania 19146, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adsorption Hydrogels / chemical synthesis* Hydrogen Bonding Macromolecular Substances Models, Molecular Molecular Structure Polymers Temperature Tensile Strength Water / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Hydrogels; 0/Macromolecular Substances; 0/Polymers; 7732-18-5/Water |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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