Document Detail

A new strategy for mapping the human genome.
MedLine Citation:
PMID:  3023616     Owner:  NLM     Status:  MEDLINE    
Recent advances in agarose gel electrophoresis of large DNA fragments raise the possibility of an entirely new approach to mapping mammalian genomes. In this article is discussed the potential of this technology for tackling problems such as construction of linkage maps, identifying chromosome translocation breakpoints, and moving from linked markers to genes causing diseases such as the muscular dystrophies and Huntington's chorea.
D J Shaw
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical genetics     Volume:  23     ISSN:  0022-2593     ISO Abbreviation:  J. Med. Genet.     Publication Date:  1986 Oct 
Date Detail:
Created Date:  1986-12-31     Completed Date:  1986-12-31     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985087R     Medline TA:  J Med Genet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  421-4     Citation Subset:  IM    
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MeSH Terms
Chromosome Mapping*
Chromosomes, Human / physiology*
DNA / genetics
DNA Restriction Enzymes
Electrophoresis, Agar Gel
Genetic Diseases, Inborn / genetics
Linkage (Genetics)
Reg. No./Substance:
9007-49-2/DNA; EC 3.1.21.-/DNA Restriction Enzymes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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