Document Detail


A new stent with streamlined cross-section can suppress monocyte cell adhesion in the flow disturbance zones of the endovascular stent.
MedLine Citation:
PMID:  25434694     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We proposed a new stent with streamlined cross-sectional wires, which is different from the clinical coronary stents with square or round cross-sections. We believe the new stent might have better hemodynamic performance than the clinical metal stents. To test the hypothesis, we designed an experimental study to compare the performance of the new stent with the clinical stents in terms of monocyte (U-937 cells) adhesion. The results showed that when compared with the clinical stents, the adhesion of U-937 cells were much less in the new stent. The results also showed that, when Reynolds number increased from 180 (the rest condition for the coronary arteries) to 360 (the strenuous exercise condition for the coronary arteries), the flow disturbance zones in the clinical stents became larger, while they became smaller with the new stent. The present experimental study therefore suggests that the optimization of the cross-sectional shape of stent wires ought to be taken into consideration in the design of endovascular stents.
Authors:
Zengsheng Chen; Fan Zhan; Jun Ding; Xiwen Zhang; Xiaoyan Deng
Related Documents :
1089174 - Continuous sutures in replacement of mitral and tricuspid valves with prostheses.
3105174 - Isolated amyloidosis of the atrioventricular valves. a study of one case, curiously ass...
23291424 - The cost of coils implanted in aneurysms: 2 years of clinical data.
24682764 - On the decellularization of fresh or frozen human umbilical arteries: implications for ...
11175084 - Diagnosis of coronary artery fistula confirmed by intravenous contrast echocardiography.
11745054 - Heart rescue in acute left main coronary artery occlusion with cabg using initial retro...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-12-1
Journal Detail:
Title:  Computer methods in biomechanics and biomedical engineering     Volume:  -     ISSN:  1476-8259     ISO Abbreviation:  Comput Methods Biomech Biomed Engin     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-12-1     Completed Date:  -     Revised Date:  2014-12-2    
Medline Journal Info:
Nlm Unique ID:  9802899     Medline TA:  Comput Methods Biomech Biomed Engin     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-7     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Ameloblastic carcinoma with features of ghost cell odontogenic carcinoma in a patient with suspected...
Next Document:  A Large-scale Cross-sectional Study of ALK Rearrangements and EGFR Mutations in Non-small-cell Lung ...