Document Detail

A new simplified method for calculating mean mitral pressure gradient.
MedLine Citation:
PMID:  17563098     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Mean mitral valve pressure gradient (MVPG) is one of the key measures of the severity of mitral stenosis. The method for calculating MVPG, however, is complex and time consuming. The purpose of this study is to establish a new simple method for calculating MVPG. METHODS: Hemodynamic data were analyzed in 105 patients who underwent percutaneous balloon mitral valvuloplasty (PBMV). A new simplified method for calculating mitral pressure gradient was proposed, i.e., mean MVPG = MLAP - LVEDP/2, where MLAP is mean left atrial pressure, and LVEDP is left ventricular end-diastolic pressure. RESULTS: MVPGs derived from the standard and the new method were 13.28 +/- 7.42 mm Hg and 13.50 +/- 7.93 mm Hg, respectively, and there was no significant difference between the values of these two methods (P = 0.065). The MVPG derived from the new simplified method correlated closely with that calculated by the standard approach (r = 0.975, P < 0.001). Moreover, there was no significant difference between mitral valve areas (MVA) derived from the standard and the new approach either before or after PBMV in the 38 patients in whom cardiac output was measured. CONCLUSION: We conclude that mitral pressure gradient can be calculated reliably with our new simplified method.
Wei Cui; Ruping Dai; Gejun Zhang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  70     ISSN:  1522-1946     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-05     Completed Date:  2008-02-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  754-7     Citation Subset:  IM    
Copyright Information:
(c) 2007 Wiley-Liss, Inc.
Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
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MeSH Terms
Balloon Dilatation / methods
Blood Pressure*
Mitral Valve / physiopathology*
Mitral Valve Stenosis / physiopathology*,  therapy
Severity of Illness Index
Comment In:
Catheter Cardiovasc Interv. 2007 Nov 1;70(5):758-9   [PMID:  17960649 ]

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