Document Detail


A new semiautomated algorithm to quantify Holter-detected myocardial ischemia: preliminary experience in the Trimetazidine European Multicenter trial (TEMS).
MedLine Citation:
PMID:  2093379     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Holter-detected myocardial ischemia, either painful or painless, is an important issue in the functional and prognostic evaluation of coronary patients. This paper describes one of the first attempts to reliably quantify the duration and severity of the ischemic ST-segment changes over a given period of time; the algorithm described here provides physicians with a global index of ischemia that is the total ischemic area, namely, the integral of ST-segment depression or elevation over time (expressed in mm x min). The diagnostic and prognostic power of this new index remains to be established and to be compared with the actually used simple measurements, i.e., the number and duration of ischemic events.
Authors:
J M Detry; R Fesler; T Berckmans; P Leclercq
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy     Volume:  4 Suppl 4     ISSN:  0920-3206     ISO Abbreviation:  Cardiovasc Drugs Ther     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1991-06-27     Completed Date:  1991-06-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8712220     Medline TA:  Cardiovasc Drugs Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  841-6     Citation Subset:  IM    
Affiliation:
Division of Cardiology, University of Louvain, Saint-Luc University Hospital, Brussels, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Algorithms*
Angina Pectoris / diagnosis*,  drug therapy
Automation
Circadian Rhythm
Double-Blind Method
Electrocardiography, Ambulatory*
Exercise Test
Humans
Trimetazidine / therapeutic use
Chemical
Reg. No./Substance:
5011-34-7/Trimetazidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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