Document Detail

A new score for predicting neonatal very low birth weight mortality risk in the NEOCOSUR South American Network.
MedLine Citation:
PMID:  16049510     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To develop and validate a model for very low birth weight (VLBW) neonatal mortality prediction, based on commonly available data at birth, in 16 neonatal intensive care units (NICUs) from five South American countries. STUDY DESIGN: Prospectively collected biodemographic data from the Neonatal del Cono Sur (NEOCOSUR) Network between October 2000 and May 2003 in infants with birth weight 500 to 1500 g were employed. A testing sample and crossvalidation techniques were used to validate a statistical model for risk of in-hospital mortality. The new risk score was compared with two existing scores by using area under the receiver operating characteristic curve (AUC). RESULTS: The new NEOCOSUR score was highly predictive for in-hospital mortality (AUC=0.85) and performed better than the Clinical Risk Index for Babies (CRIB) and the NICHD risk models when used in the NEOCOSUR Network. The new score is also well calibrated - it had good predictive capability for in-hospital mortality at all levels of risk (HL test=11.9, p=0.85). The new score also performed well when used to predict in hospital neurological and respiratory complications. CONCLUSIONS: A new and relatively simple VLBW mortality risk score had a good prediction performance in a South American network population. This is an important tool for comparison purposes among NICUs. This score may prove to be a better model for application in developing countries.
Guillermo Marshall; Jose L Tapia; Ivonne D'Apremont; Carlos Grandi; Claudia Barros; Angelica Alegria; Jane Standen; Ruben Panizza; Liliana Roldan; Gabriel Musante; Aldo Bancalari; Enrique Bambaren; Jose Lacarruba; Maria E Hubner; Jorge Fabres; Marcelo Decaro; Gonzalo Mariani; Isabel Kurlat; Agustina Gonzalez;
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  25     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-08-26     Completed Date:  2006-01-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  577-82     Citation Subset:  IM    
Departamento de Salud Publica Universidad Catolica, Santiago, Chile.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Infant Mortality*
Infant, Newborn
Infant, Very Low Birth Weight*
Prospective Studies
South America / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway...
Next Document:  Prevalence and clinical implications of bone marrow involvement in pediatric anaplastic large cell l...