Document Detail


A new regimen of bowel preparation for PillCam colon capsule endoscopy: A pilot study.
MedLine Citation:
PMID:  21087902     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: Colon capsule endoscopy (CCE) represents a new diagnostic, endoscopic technology for colonic exploration. Current protocols of preparation led to discordant rates of adequate cleansing level or CCE excretion.
AIM: To evaluate the effect of a new regimen of bowel preparation for CCE on colon cleansing levels and on rate of capsule excretion.
STUDY: 60 patients were prospectively enrolled. The new regimen of preparation consisted of a split regimen of PEG administration and of a 45mL dose of sodium phosphate (NaP). Four senna tablets and a low-residue diet were also included. CCE excretion rate, colon cleansing, and accuracy were assessed.
RESULTS: Forty-six patients were included in the final analysis, 13 patients (22%) being excluded because of preparation protocol deviations and one due to CCE technical failure (2%). At CCE, bowel preparation was rated as good in 78% of patients, fair in 20% and poor in 2%. CCE excretion rate occurred in 83% of patients. CCE sensitivity and specificity for significant findings was 100% and 95%, respectively.
CONCLUSIONS: The combination of a split-dose of PEG solution with a low dose of NaP boosters resulted in high rates of adequate cleansing level and CCE excretion.
Authors:
Cristiano Spada; Cesare Hassan; Marcello Ingrosso; Alessandro Repici; Maria Elena Riccioni; Marco Pennazio; Giuseppe Alessandro Pirozzi; Nico Pagano; Paola Cesaro; Gianluca Spera; Lucio Petruzziello; Guido Costamagna
Publication Detail:
Type:  Journal Article     Date:  2010-11-18
Journal Detail:
Title:  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver     Volume:  43     ISSN:  1878-3562     ISO Abbreviation:  Dig Liver Dis     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100958385     Medline TA:  Dig Liver Dis     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  300-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Digestive Endoscopy Unit, Catholic University, Largo Francesco Vito 1, Rome, Italy.
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