Document Detail

A new prediction score for myocardial infarction: MINF SCORE.
MedLine Citation:
PMID:  19284086     Owner:  NLM     Status:  MEDLINE    
The present report aims to generate a simple and efficient non-invasive prediction system of myocardial infarction as well as evaluating of the new generated score. METHODS: 208 patients (both men and women) aged 37-75 admitted at Centre Hospitalier Coulommiers, France, were included in the study. Patients were divided into two groups, according to presence (104 patients, 63.7 +/- 9.2 years) and absence of myocardial infarction (104 patients, 58.1 +/- 12.4 years). RESULTS: Based on univariate and multivariate analyses the following parameters were selected to form the prediction model: age, lipoprotein (a), C-reactive protein, systolic blood pressure, non-HDL-Cholesterol. A new score was obtained and it was validated by the area under the ROC curve of 0.745 +/- 0.034 (95% CI = 0.681-0.804), p < 0.0001. For the newly generated score, at the cut-off point (> -0.3), we obtained the following accuracy parameters: sensibility=80%, specificity=62.5%, positive predictive values=65%, negative predictive values =78%. The mentioned parameters were superior to values of each component of the score individually analyzed. CONCLUSIONS: The newly generated system can become a useful tool in coronary risk evaluation, with direct application in clinical practice.
Teodora Mocan; Lucia Agoşton-Coldea; M Gatfossé; Sophie Rosenstingl; L C Mocan; D L Dumitraşcu
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Romanian journal of internal medicine = Revue roumaine de médecine interne     Volume:  46     ISSN:  1220-4749     ISO Abbreviation:  Rom J Intern Med     Publication Date:  2008  
Date Detail:
Created Date:  2009-03-16     Completed Date:  2009-04-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9304507     Medline TA:  Rom J Intern Med     Country:  Romania    
Other Details:
Languages:  eng     Pagination:  145-51     Citation Subset:  IM    
Department of Normal Morphology and Functions, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
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MeSH Terms
Aged, 80 and over
C-Reactive Protein / metabolism
Cross-Sectional Studies
Health Status Indicators*
Lipids / blood
Middle Aged
Myocardial Infarction / blood,  diagnosis*,  etiology*
Predictive Value of Tests
Reproducibility of Results
Risk Assessment
Risk Factors
Reg. No./Substance:
0/Lipids; 9007-41-4/C-Reactive Protein

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