Document Detail


A new polymer valve for mechanical circulatory support systems.
MedLine Citation:
PMID:  9029247     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A new low-cost artificial heart valve with easily modified dimensions according to its application was developed using segmented polyurethane (SPU). It consists of a convex frame and a concave membrane which floats in the center of the frame while working. The hydrodynamic performance of the polymer valve was compared with that of the Björk-Shiley mechanical valve using a mock circulatory testing system. The hydrodynamic performance of this valve was superior to the Björk-Shiley mechanical valve. The valve was applied to a ventricular assist device (VAD) developed in our institute. In vivo performances of these systems were tested using mongrel dogs. During the experiments, there were no complications related to malfunction of the valve. At postmortem examinations, no thrombus formation was found on the valve surface, and no embolus was detected in the kidneys. We believe this valve could prove a very useful alternative for valves of mechanical circulatory support systems (MCSS) such as VAD and TAH.
Authors:
S W Suh; W G Kim; H C Kim; B G Min
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  The International journal of artificial organs     Volume:  19     ISSN:  0391-3988     ISO Abbreviation:  Int J Artif Organs     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-06-17     Completed Date:  1997-06-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802649     Medline TA:  Int J Artif Organs     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  712-8     Citation Subset:  IM    
Affiliation:
Department of Biomedical Engineering, Seoul National University, Korea.
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MeSH Terms
Descriptor/Qualifier:
Animals
Biomechanics
Cost-Benefit Analysis
Dogs
Heart Valve Prosthesis / adverse effects,  economics,  standards*
Heart-Assist Devices / standards*
Hemoglobins / analysis
Membranes, Artificial*
Polyurethanes*
Thromboembolism / prevention & control
Chemical
Reg. No./Substance:
0/Hemoglobins; 0/Membranes, Artificial; 0/Polyurethanes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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