Document Detail

A new model for calculating auditory excitation patterns and loudness for cases of cochlear hearing loss.
MedLine Citation:
PMID:  21983133     Owner:  NLM     Status:  MEDLINE    
A model for calculating auditory excitation patterns and loudness for steady sounds for normal hearing is extended to deal with cochlear hearing loss. The filters used in the model have a double ROEX-shape, the gain of the narrow active filter being controlled by the output of the broad passive filter. It is assumed that the hearing loss at each audiometric frequency can be partitioned into a loss due to dysfunction of outer hair cells (OHCs) and a loss due to dysfunction of inner hair cells (IHCs). OHC loss is modeled by decreasing the maximum gain of the active filter, which results in increased absolute threshold, reduced compressive nonlinearity and reduced frequency selectivity. IHC loss is modeled by a level-dependent attenuation of excitation level, which results in elevated absolute threshold. The magnitude of OHC loss and IHC loss can be derived from measures of loudness recruitment and the measured absolute threshold, using an iterative procedure. The model accurately fits loudness recruitment data obtained using subjects with unilateral or highly asymmetric cochlear hearing loss who were required to make loudness matches between tones presented alternately to the two ears. With the same parameters, the model predicted loudness matches between narrowband and broadband sound reasonably well, reflecting loudness summation. The model can also predict when a dead region is present.
Zhangli Chen; Guangshu Hu; Brian R Glasberg; Brian C J Moore
Related Documents :
14632443 - Nearest neighbor search in general metric spaces using a tree data structure with a sim...
17668213 - Multiple pattern matching: a markov chain approach.
22372863 - Species distribution models as a tool to estimate reproductive parameters: a case study...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-09-29
Journal Detail:
Title:  Hearing research     Volume:  282     ISSN:  1878-5891     ISO Abbreviation:  Hear. Res.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-05     Completed Date:  2012-04-02     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  7900445     Medline TA:  Hear Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  69-80     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier B.V. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acoustic Stimulation
Auditory Threshold
Cochlea / pathology,  physiopathology*
Hair Cells, Auditory, Inner / pathology
Hair Cells, Auditory, Outer / pathology
Hearing Loss, Sensorineural / pathology,  physiopathology*,  psychology*
Loudness Perception*
Models, Neurological*
Pattern Recognition, Physiological*
Grant Support
G0701870//Medical Research Council; //Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Viral epidemiology of acute exacerbations of chronic obstructive pulmonary disease.
Next Document:  Whispering gallery mode biosensor quantification of fibronectin adsorption kinetics onto alkylsilane...