Document Detail

A new method to evaluate the elastic modulus of cortical bone by using a combined computed tomography and finite element approach.
MedLine Citation:
PMID:  20304390     Owner:  NLM     Status:  MEDLINE    
This study attempted to estimate the elastic modulus of cortical specimens directly from the computed tomography (CT) number (CT). Cubic specimens of fresh bovine femora were tested under compressive loading. The corresponding three-dimensional mesh models of these specimens were established with the aid of CT images. The elastic modulus of each element was determined using the following transfer formula: E=Ax(CT)(B). The A and B were determined by matching the simulation results with the experimental force-displacement curves. An optimization approach was used to match the entire specimen sets between simulations and experiments. The results indicated that the elastic modulus of cortical bone can be effectively estimated using a power relationship (E=1.26 x 10(-3) x (CT)(1.93)) directly from the CT number. This procedure eliminates the need to determine the bone density, and therefore reduces the computational time required to define mechanical properties in finite element methods.
Heng-Li Huang; Ming-Tzu Tsai; Dan-Jae Lin; Chi-Sheng Chien; Jui-Ting Hsu
Publication Detail:
Type:  Journal Article     Date:  2010-03-20
Journal Detail:
Title:  Computers in biology and medicine     Volume:  40     ISSN:  1879-0534     ISO Abbreviation:  Comput. Biol. Med.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-05     Completed Date:  2010-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1250250     Medline TA:  Comput Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  464-8     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Ltd. All rights reserved.
School of Dentistry, College of Medicine, China Medical University, Taichung, Taiwan, ROC.
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MeSH Terms
Compressive Strength
Elastic Modulus / physiology*
Femur / physiology*,  radiography*
Finite Element Analysis*
Stress, Mechanical
Tomography, X-Ray Computed*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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