| A new method to close the gastrotomy by using a cardiac septal occluder: long-term survival study in a porcine model. | |
| | |
MedLine Citation:
|
PMID: 17905027 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
INTRODUCTION: Closure of the gastrotomy when performing transgastric procedures is one of the most challenging steps to overcome. Several methods of gastric closure have been described, but a simple and safe technique is still lacking. AIM: To evaluate the technical feasibility and safety of a new method of endoscopic gastric closure using a nitinol septal occluder in a porcine survival model. DESIGN: Endoscopic animal experimental study in a porcine survival model. MATERIALS AND METHODS: In 6 male pigs under general anesthesia, a 1-cm full-thickness gastrotomy was performed on the anterior body of the stomach and closed with a nitinol septal occluder (Occlutech). Postoperative follow-up included endoscopy and laparoscopy at 1, 2, 4, and 6 weeks after the initial procedure and endoscopy alone at weeks 8, 10, and 12. RESULTS: All of the gastrotomy closures with the septal occluder were successful. At follow-up endoscopy and laparoscopy there were no signs of adhesions, peritonitis, or perigastric abscess formation at the gastrotomy site. At 12 weeks, 5 of 6 animals were thriving, with appropriate weight gain. CONCLUSIONS: Endoscopic gastrotomy closure with a septal occluder is technically feasible, safe, and effective in a survival porcine model. |
| | |
Authors:
|
Silvana Perretta; Stefano Sereno; Antonello Forgione; Bernard Dallemagne; Dimitri Coumaros; Cristoph Boosfeld; Clemens Moll; Jacques Marescaux |
Related Documents
:
|
507897 - Echocardiographic findings of large patent ductus arteriosus in the very low birthweigh... 78327 - Plasma-prostaglandins in pre-term neonates before and after treatment for patient ductu... 12082467 - Mean arterial pressures during the first 24 hours of life in < or = 600-gram birth weig... 8237357 - Asymptomatic reopening of ductus arteriosus after successful closure by indomethacin in... 11095637 - Rod-mediated increment threshold functions in infants. 21639927 - Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18... |
Publication Detail:
|
Type: Evaluation Studies; Journal Article |
Journal Detail:
|
Title: Gastrointestinal endoscopy Volume: 66 ISSN: 0016-5107 ISO Abbreviation: Gastrointest. Endosc. Publication Date: 2007 Oct |
Date Detail:
|
Created Date: 2007-10-01 Completed Date: 2008-01-03 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0010505 Medline TA: Gastrointest Endosc Country: United States |
Other Details:
|
Languages: eng Pagination: 809-13 Citation Subset: IM |
Affiliation:
|
Institut de Recherche contre les Cancers de l'Appareil Digestif-European Institute of Telesurgery, University of Strasbourg, Strasbourg, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alloys* Animals Disease Models, Animal Equipment Design Feasibility Studies Follow-Up Studies Gastroscopes* Gastroscopy / methods*, mortality Heart Septum Male Prosthesis Design Prosthesis Implantation / instrumentation*, mortality Stents Stomach / surgery* Survival Analysis Swine Time Factors Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Alloys; 52013-44-2/nitinol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Human application of a metallic stent covered with a paclitaxel-incorporated membrane for malignant ...
Next Document: EUS-guided portal vein carbon dioxide angiography: a pilot study in a porcine model.